Coumarins and derivatives
Medchemexpress LLC 6-Bromocoumarin | 19063-55-9 | 225.04 | 1 G
6-Bromocoumarin is a potential anti-bacterial agent that exhibits affinity for α and β estrogen receptors. It does not inhibit 17β-HSD1 and is intended for research use only.
- Potential anti-bacterial agent
- Exhibits affinity for α and β estrogen receptors
- Does not inhibit 17β-HSD1
- High purity of 98.51%
- White to off-white solid appearance
- Molecular weight of 225.04
Medchemexpress LLC 3-Acetylcoumarin | 3949-36-8 | 97.0% | 188.18 | 25 G
3-Acetylcoumarin is a chemical compound that exhibits acaricidal activity against *Tetranychus cinnabarinus*.
- Exhibits acaricidal activity against *Tetranychus cinnabarinus*
- Molecular weight of 188.18
- Appears as a light yellow to yellow solid
- Recommended storage conditions ensure product stability
eMolecules 51690-26-7 | Coumarin-6-carboxaldehyde | Apollo Scientific | MFCD01941322 | 174.155 | C10H6O3 | 95.000 | O=Cc1ccc2oc(=O)ccc2c1 | 1g | 562441556
Coumarin-6-carboxaldehyde | Apollo Scientific | 51690-26-7 | MFCD01941322 | 174.155 | C10H6O3 | 95.000 | O=Cc1ccc2oc(=O)ccc2c1 | 1g | 562441556
Medchemexpress LLC Coumarin boronic aci 10mg
Coumarin boronic acid is a fluorescent probe The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm respectively Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification[1]
Cayman Chemical 7-MethoxycoumarIn 5g
A coumarin with diverse biological activities; reduces A23187-induced release of PGE2 and LTC4 in isolated mouse peritoneal macrophages; active against S. aureus, S. epidermidis, B. subtilis, S. lutea, and V. cholera (MICs = 0.5, 0.75, 0.75, 0.75, and 0.5 mg/ml, respectively); reduces formalin-induced paw licking and biting responses in mice at 3 and 7.5 mg/kg
Medchemexpress LLC 7-methoxycoumarin-3-carboxylic acid | 20300-59-8 | MFCD00452770 | ≥97.0% | 220.18 | C11H8O5 | 1 G
7-Methoxycoumarin-3-carboxylic acid is a coumarin-derived fluorescent dye used to label peptides and other biomolecules for biochemical assays and HPLC derivatization. It is supplied as a solid with high purity and is prepared as a DMSO stock for use in fluorescence-based assays; handle and store protected from light.
- Excitation and emission in the near-UV/blue range (Ex ≈345-355 nm, Em ≈405-450 nm).
- Suitable for peptide labeling and HPLC derivatization.
- High purity appropriate for analytical applications (~97.0%).
- Soluble in DMSO (≈8 mg/mL with sonication and warming).
- Store protected from light; in solution, keep frozen for extended stability.
![Medchemexpress LLC Methanesulfonamide, N-[2-chloro-5-[4-[[(1R)-1-phenylethyl]amino]-6-quinazolinyl]-3-pyridinyl]- | 2791417-66-6 | 99.9% | 453.94 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000395426.png-250.jpg)
Medchemexpress LLC Methanesulfonamide, N-[2-chloro-5-[4-[[(1R)-1-phenylethyl]amino]-6-quinazolinyl]-3-pyridinyl]- | 2791417-66-6 | 99.9% | 453.94 | 25 MG
MTX-531 is an oral drug that inhibits EGFR and PI3K, demonstrating anti-tumor effects. It also acts as a weak agonist of PPARγ, helping to alleviate hyperglycemia induced by PI3K inhibitors. This compound shows good tolerability in in vivo studies, without causing hyperglycemia, a common side effect of PI3K inhibitors.
- Inhibits EGFR with an IC50 of 14.7 nM, and PI3K with IC50 values ranging from 1.1 nM to 233 nM.
- Demonstrates anti-tumor effects, suppressing tumor proliferation and growth.
- Acts as a weak agonist of PPARγ with an IC50 of 2.5 μM, which helps to alleviate hyperglycemia.
- Indicates excellent tolerance in mice and the absence of hyperglycemia in vivo.
AdipoGen Coumarin 7
Chemical. CAS 27425-55-4. Formula C20H19N3O2. Molecular Weight 333.38. Coumarin 7 is a greenish yellow fluorescent dye. It has good heat resistance and light resistance, good migration resistance and high tinting strength with wide application. Coumarin 7 is a laser dye that is used as green phosphorescent dopant material for organic light-emitting diodes OLED. Its derivatives are used in medicine and chemistry. Spectral Data lambdaabs 438nm, lambdaem 266nm/355nm, lambdaex 490nm, lambdalaser 520nm.
Selleck Chemical LLC Dicoumarol S4299-200mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor and used as an anticoagulant by interfering with the metabolism of vitamin K
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | MFCD00037563 | 5 G
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that covalently binds to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). It is for research use only.
- Molecular weight: 220.18
- Formula: C11H8O5
- Appearance: Solid
- Color: White to off-white
- Emission (Em): 450
- Excitation (Ex): 415
Cayman Chemical 7-AzIdo-4-methylcoumarIn 1mg
A fluorescent H2S probe; ex/em = 340/445 nm, respectively; selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species
eMolecules 2442-31-1 | 8-hydroxycoumarin | MFCD18450722 | 1g
ChemScene | 2-(Trifluoromethyl)quinoline-3-carboxylic acid | 100mg | 714138746 | CS-0247965 | 587886-26-8 | MFCD01862086 | 241.169 | C11H6F3NO2
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Medchemexpress LLC 8-Hydroxycoumarin | 2442-31-1 | 99.6% | 162.14 | 1 ML
8-Hydroxycoumarin is an intermediate in the microbial transformation of quinolone. It is for research use only and not sold to patients.
- Intermediate in microbial transformation of quinolone
- Suitable for laboratory research applications
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 1g
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Medchemexpress LLC Coumarin 480 (Coumarin 102) | 41267-76-9 | MFCD00041844 | 100.0% | 255.31 g·mol⁻¹ | C16H17NO2 | 50 MG
Coumarin 480 is a fluorescent coumarin-class laser dye supplied as a high-purity research reagent. It is intended for photophysical studies, fluorescent labeling, and laser applications. Certificate of analysis and safety data sheet are available from the manufacturer.
- Laser dye suitable for photophysical and fluorescence studies.
- High purity: 99.95%.
- Solid form supplied in small laboratory pack sizes (25 mg, 50 mg, 100 mg; larger sizes available on request).
- Documented safety and quality data available (COA and SDS).
- Molecular formula C16H17NO2; molecular weight 255.31 g·mol⁻¹.